Affinity DataIC50: 8nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (Trypanosoma cruzi) Trypanothione reductaseMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant Escherichia coli IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric as...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant Escherichia coli IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric as...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against DOXP reductoisomeraseMore data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2VH5Q21PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2VH5Q21PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant Escherichia coli IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric as...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibitory concentration against DOXP reductoisomeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2FJ2GB6PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2FJ2GB6PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (Trypanosoma cruzi) Trypanothione reductaseMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 30nMAssay Description:Inhibition of Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2XD12NVPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2XD12NVPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of Escherichia coli DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of Escherichia coli DxrMore data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q29K4CVJPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q29K4CVJPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataIC50: 32nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2057HKTPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2057HKTPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataIC50: 42nMpH: 7.5Assay Description:Assays were performed in 50 mM Tris/HCl buffer, pH 7.5, containing 3 mM MgCl2 and 2 mM DTT. The concentrations of NADPH and DXP were 0.15 and 0.5 mM ...More data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2XS5T4JPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2XS5T4JPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q22F7N24PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q22F7N24PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataIC50: 48nMAssay Description:Antagonism of norepinephrine induced contraction of rat isolated thoracic aorta.More data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 49nMAssay Description:Antagonism of norepinephrine induced contraction of rat isolated thoracic aorta.More data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibitory concentration against DOXP reductoisomeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of Escherichia coli DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibitory concentration against DOXP reductoisomeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of Escherichia coli M15 recombinant IspC using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric analysisMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium smegmatis (strain ATCC 700084 / mc(2...)
Universit£ de Strasbourg/CNRS
Curated by ChEMBL
Universit£ de Strasbourg/CNRS
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of Mycobacterium smegmatis DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 99nMAssay Description:Inhibition of Escherichia coli DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 99nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against DOXP reductoisomeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Inhibition of Escherichia coli DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of Escherichia coli M15 recombinant IspC using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 156nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant Escherichia coli IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric as...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Antagonism of norepinephrine induced contraction of rat isolated thoracic aorta.More data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 178nMAssay Description:Inhibitory concentration against DOXP reductoisomeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of Escherichia coli M15 recombinant IspC using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant Escherichia coli IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric as...More data for this Ligand-Target Pair
Affinity DataIC50: 229nMAssay Description:Inhibitory concentration against DOXP reductoisomeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 257nMAssay Description:Inhibitory concentration against DOXP reductoisomeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 282nMAssay Description:Inhibitory concentration against DOXP reductoisomeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant Escherichia coli IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric as...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of Escherichia coli M15 recombinant IspC using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 311nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 311nMAssay Description:Inhibition of Escherichia coli DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 313nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of Escherichia coli M15 recombinant IspC using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric analysisMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium smegmatis (strain ATCC 700084 / mc(2...)
Universit£ de Strasbourg/CNRS
Curated by ChEMBL
Universit£ de Strasbourg/CNRS
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of Mycobacterium smegmatis DSM 43756 ATCC 19420 N-terminal his-tagged DXR expressed in XL1-blue Escherichia coli using NADPH and DXP as su...More data for this Ligand-Target Pair
Affinity DataIC50: 396nMAssay Description:Inhibition of Escherichia coli DXRMore data for this Ligand-Target Pair
Affinity DataIC50: 396nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair